[R]esearchers believe the process could also have a more traditional therapeutic effect. Psilocybin helps deactivate an area of the brain associated with the  ”pathological brooding” of depression; reducing connectivity in these parts of the brain may actually help alleviate depression’s “rigidly pessimistic” way of thinking.

Weirdly enough, my last mushroom trip (and my last trip on anything) seemed to hyperactivate my “pathological brooding”. I spent the entire trip fighting off this tremendous cycle of terrible thoughts about my childhood and my parents and how I was alone in the world with no one to help or protect me.

That was a year and a half ago and I’ve been too scared to trip ever since.